Brown University Tripathi Lab
Scalable Bioengineering Solutions For Diagnostics and Live Science
While interning at the Tripathi Lab, I worked to bring more affordable and accessible medical treatments to underserved areas and communities without adequate testing capabilities.
As part of the Clinical Diagnostics and Automation team, I automated over 20 experiments for 4 studies using a JANUS G3 Robotic Liquid Handler and QSight 220 Triple Quadrupole LC/MS/MS Mass Spectrometer.
I also used COMSOL, a Multiphysics simulation software, to design a 3-D printable Microfluidic chip to replicate the vascular structure of the human Ovary in helping analyze various treatment regimens for the Caov-3 Ovarian Cancer cell line.
Research Studies
- LC-MS/MS Quantification of PARP-inhibitor Uptake for Validating an Ovarian Tumor on a Chip; Using a Microfluidic chip to test treatment efficacy for Ovarian Cancer (Abstract accepted for presentation at the 2024 Society of Laboratory Automation and Screening (SLAS) International Conference)
- Electric field-Assisted Automatable Dried Blood Spots Sample Preparation device for Neonatal Abstinence Syndrome Screening; Optimized 7 drugs of abuse on LC-MS/MS to test drug levels in newborns (Abstract accepted for presentation at the 2024 SLAS International Conference)
- Capillary Flow Sample Preparation Device For Amphetamine Detection Using LC-MS/MS; A Microfluidic device using capillary flow to detect levels of Amphetamine (Abstract accepted for presentation at the 2024 SLAS International Conference)
- Electric-field Assisted Sample Preparation of Whole Blood and Dried Blood Spots for Steroid Quantification using LC-MS/MS; Device to cycle current through steroid samples in preparation for Mass Spec. Analysis (Abstract accepted for presentation at the 2024 SLAS International Conference)
Review Papers
- Dried Blood Spots for Quantitative Clinical Translation: A Review; Focused on the novelty of Dried Blood Spots and how they can be used in Disease Diagnosis and Detection (In Publication Process)
- A Review of Automated Workflow for LC-MS/MS Sample Preparation using Robotic Liquid Handlers; Reviewed the applications of Robotic Liquid Handlers for automated sample preparation and testing (In Publication Process)
Wayne State WAPO Lab
Working for What’s Possible & What’s Positive.
At the WAPO lab, I used Brain-Computer Interfaces (BCI) and paired them with algorithms to implement emotion detection and treatment programs in low-resource communities
I also researched how Brain-Computer Interface hardware can be used to detect brainwave activity from various locations around the head.
From this EEG data, I created an algorithm to detect various mental states and emotions, such as, stress, depression, and anxiety.
With this low-cost hardware from OpenBCI, this algorithm can be paired with headsets and used in local clinics.
I authored a Science Communication Article about my work, see it below!
Farhan Haque 